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We all hate pain for clouding our minds with distressing throbbing feeling and spoiling all our plans. Of course, we do understand that pain starts to inform us of real or potential danger threatening our health, actually, pain is the herald of our instinct of self-preservation. Feeling pain we withdraw from the source of danger as soon as possible even before we realize the whole situation. This way our body protects itself from severe injury or tries to diminish the damage caused.

Pain appears when needed and disappears when the threat is averted or the injury is healed. This is a normal state of affairs. Alas, in several cases pain can stay for days, weeks and even months and patients in pain suffer this awful torture round the clock! No-one can live like this without a swift and effective medical help. You will be astonished to hear that conventional medicine knows no medication just as effective and rapid as opioid pain relievers.

Hydrocodone, a semisynthetic narcotic pain killer and hydrogenated ketone derivative, is very similar to other Phenanthrene derivatives, such as Codeine. As a rule, Hydrocodone is recommended as a powerful pain killer in traditional combinenation with Acetaminophen, Ibuprofen or Aspirin to overcome pain. If you take Hydrocodone, you can expect to feel better within a few minutes. Of course, for patients there is a great temptation to get discount Hydrocodone and start taking it immediately.

Please, realize that Hydrocodone is a very tricky medicine. You should remember many significant facts about it before you decide to get cheap Hydrocodone without prescription and make it your regular analgesic!

Unlike other opioid pharmaceuticals Hydrocodone is often prescribed as an effective antitussive when combined with phenylephrine, pseudoephedrine, phenylpropanolamine, guaifenesin, pyrilamine, pheniramine or chlorpheniramine. The amazing fact is that as a regular antitussive, Hydrocodone is approximately 3 times as potent as codeine on a weight for weight basis.

Now it is high time to speak about Hydrocodone troubles. First of all, Hydrocodone is often scorned for being addictive. The thing is that Hydrocodone produces drug dependence of the Morphine type typical for all opioid pills and that is why it is one of the most abused narcotics. What is more, if Hydrocodone is used repeatedly, psychic dependence, physical dependence and Hydrocodone tolerance is a question of time! No wonder Hydrocodone and other active ingredients of the Hydrocodone containing drugs should be prescribed and administered with the same degree of caution typical for other narcotic drugs.

The safety and efficacy of Hydrocodone bitartrate as a general antitussive agent is a doubtful affair in children younger than 6 years of age. As for the extended-release Hydrocodone containing medicines, they are forbidden in children younger than 6 years of age. The extended-release Hydrocodone containing antitussives should be used with great caution even in children over 6 years of age due to the risk of bad respiratory depression. Warning! The risk of fatal respiratory depression is increased with Hydrocodone high dosage, overdosage or intake of other respiratory depressants!

Please, keep in mind that no Hydrocodone-containing antitussive agent has clinically proved to be safe and effective for use in children under 6 years of age! With all that you can find some firms who manufacture and/or distributed Hydrocodone-containing cough suppressant agents without FDA approval that are labeled for use in children as young as 2 years of age! Never risk giving meds of that kind to your children! Please, do not fail to remember that overdosage and toxicity including death have been reported in children under 2 years of age receiving nonprescription pills containing antihistamines, cough suppressants, expectorants and nasal decongestants alone or in combination for relief of symptoms of upper respiratory tract infection.

Because of the dose-dependent respiratory-depressant effects of Hydrocodone, this kind of therapy should be carefully considered in pediatric patients! Parents and medical people should consciously view all potential benefits and risks of Hydrocodone before starting the treatment. Please, do not forget that you should be very careful, especially in those with that may impede adequate respiration (e.g., croup etc.).

The matter is that there is very little data showing the efficiency of these pills in this age group of children. What is more, appropriate dosages approved by the FDA for the basic therapy of cold and cough have not been estimated. Actually, the FDA considers that nonprescription Hydrocodone-containing cough suppressants should not be used in children under 2 years of age. Data collection as to the safety and efficacy of these pharmaceuticals in older children is still going on, too. Nevertheless, now it is absolutely clear that children of 2-3 years of age are at increased risk of Hydrocodone overdose, that is exactly why the main part of manufacturers of oral nonprescription cough and cold preparations recently have agreed to reconsider the Hydrocodone product labeling and point out that such medications should not be perscribed in children under 4 years of age.

Another flaw of Hydrocodone as a pain reliever is the effect it has in old patients. Clinical researches of Hydrocodone proved that patients over 65 often develop numerous Hydrocodone adverse reactions, suffer from bothersome Hydrocodone withdrawal, need a smaller intake to overdose this opioid medication and can easily get addicted to Hydrocodone. As for Hydrocodone in compound pharmaceuticals like extended-release cough suppressant suspension, the medical studies did not include sufficient numbers of humans over 65 years of age to know for sure whether any severe problems.

At the same time other medical studies state there is no age-related difference in safety or response to Hydrocodone, some care should be taken in dosage selection in geriatric patients. The best way out for elderly persons is to take Hydrocodone in the smallest dosage possible within the shortest period of time necessary for diminishing the major symptoms. Please, do not forget that because of decreased hepatic, renal and/or cardiac function and of long-term drug therapy in geriatric patients, the manufacturers state that old men and women should always receive minimal dosages of this medication.

Your general practitioner should explain you that Hydrocodone is eliminated in urine, that is why the risk of toxicity is increased in humans with impaired renal function. Please, bear in mind that you should inform your general practitioner about any kidney and/or liver problems you had in the past or have now.

Probably you will be shocked to learn that Hydrocodone alone is classified as a Schedule II opioid drug requiring strict medical control, while Hydrocodone in combinations is classified as a Schedule III opioid med. This means that psychic and/or physical dependence and tolerance develop upon repeated administration of Hydrocodone; therefore, Hydrocodone should be recommended and administered with caution.

Hydrocodone is very powerful in managing pain, no wonder many men and women get emotionally attached to it. Fortunately psychic dependence is unlikely to from when Hydrocodone containing medicines are recommended for a short time as a cough suppressant.

Physical dependence is a severe medical condition in which continued administration of Hydrocodone is needed to prevent the appearance of a bothersome withdrawal syndrome. As a rule this kind of dependence is formed after clinically significant Hydrocodone doses after several weeks of continued oral opioid drug use. Sorry to inform you that some degree of physical dependence may develop only after a few days of Hydrocodone therapy!

Hydrocodone overdose is always a bad and even fatal condition. Severe overdosage with Hydrocodone is characterized by:

- respiratory depression (like a decrease in respiratory rate and/or tidal volume, Cheyne-Stokes respiration, cyanosis),
- extreme somnolence progressing to stupor or coma,
- skeletal muscle flaccidity,
- cold and clammy skin,
- bradycardia and hypotension;
- apnea,
- circulatory collapse, cardiac arrest,
- death.

Seek medical help as soon as possible if you or any patient you know has taken too many pills of Hydrocodone! Save a human life!

Primary attention in overdose people should be given to the reestablishment of normal respiratory exchange, even if the patent needs the institution of assisted or controlled ventilation. Up-to-date pharmacology offers us narcotic antagonists such as Naloxone hydrochloride as specific antidotes for dangerous respiratory depression which may result from overdose or personal sensitivity to Hydrocodone or other narcotic meds. As a rule, an appropriate dose of Naloxone hydrochloride is administered by the intravenous route while the MDs do their best to reestablish the normal respiratory exchange. Please, bear in mind that it is dangerous to use antagonists in the absence of clinically significant respiratory depression! What is more, gastric emptying may turn out to be very useful in removing unabsorbed Hydrocodone and changing the overdose patient’s state for better. That is exactly what you should start with while the ambulance is on the way!